A mitochondrial DNA mutation passed down through the maternal line in some Venezuelan families has been linked to severe ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues have used mitochondrial base editing (mtBE) to successfully edit harmful ...

The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...

Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might ...

By Tarun Sai Lomte New evidence from Indian patients shows that severe COVID-19 is associated with distinct mitochondrial ...

Many mitochondrial diseases have been difficult to study and treat due to the inherent challenges in accessing mitochondrial DNA (mtDNA). Now, researchers have optimized mitochondrial-targeted ...

New molecule halts mitochondrial DNA loss before it triggers inflammation. When environmental stress harms DNA, it can set off a cascade of failures linked to heart conditions, neurodegeneration and ...

Despite being renowned as the “powerhouse of the cell,” mitochondria can also be a source of heartache for those living with mitochondrial disease—especially when planning to have children. Because ...

How One Tiny Cellular Structure Holds the Key to Better Health & Longevity — and How You Can Harness It ...